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慢性髓原白血病細(xì)胞K-562
??【編號】：K-562

??【名稱】：慢性髓原白血病細(xì)胞K-562

??【規(guī)格】：株

??【價格】：1800

　　K-562人慢性髓原白血病細(xì)胞

　　描述：連續(xù)細(xì)胞株K-562由Lozzio從一位臨終的53歲女性慢性骨髓性白血病患者的胸水中建立。 細(xì)胞被歸入高度未分化的粒性白細(xì)胞類。 Anderson等對其表面膜性質(zhì)的研究表明，K-562是一株人類紅白血病細(xì)胞。 K-562細(xì)胞株在自然殺傷分析中廣泛作為高敏感的體外受體。 See Pross等將它用于NK細(xì)胞的體外詳細(xì)檢測，包括NK細(xì)胞活性的數(shù)學(xué)量化。 K-562母細(xì)胞是多能性，造血惡性細(xì)胞，它能自發(fā)分化成可識別的紅血球祖細(xì)胞、粒性白細(xì)胞、單核細(xì)胞等。它是EBNA陰性的。
　　動物種別：人
　　性別：女
　　組織來源：骨髓；慢性骨髓性白血病(CML)
　　形態(tài)：淋巴母細(xì)胞
　　培養(yǎng)基和添加劑：IMDM培養(yǎng)基(GIBCO,貨號12200036)，90%；優(yōu)質(zhì)胎牛血清，10%。 氣相：空氣，95%；二氧化碳，5%。 溫度：37攝氏度。
　　供應(yīng)限制：A。僅供研究之用。
　　REFERENCE：Koeffler HP , Golde DW . Human myeloid leukemia cell lines: a review. Blood 56: 344-350, 1980. PubMed: 6996765 Ortaldo JR , et al. Specificity of natural cytotoxic reactivity of normal human lymphocytes against a myeloid leukemia cell line. J. Natl. Cancer Inst. 59: 77-82, 1977. PubMed: 69036 Lozzio CB , Lozzio BB . Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. Blood 45: 321-334, 1975. PubMed: 163658 Lozzio BB , Lozzio CB . Properties and usefulness of the original K-562 human myelogenous leukemia cell line. Leuk. Res. 3: 363-370, 1979. PubMed: 95026 Andersson LC , et al. K562--a human erythroleukemic cell line. Int. J. Cancer 23: 143-147, 1979. PubMed: 367973 Lozzio BB , et al. A multipotential leukemia cell line (K-562) of human origin. Proc. Soc. Exp. Biol. Med. 166: 546-550, 1981. PubMed: 7194480 Dimery IW , et al. Variation amongst K562 cell cultures. Exp. Hematol. 11: 601-610, 1983. PubMed: 6576909 Chan YJ , et al. Two distinct upstream regulatory domains containing multicopy cellular transcription factor binding sites provide basal repression and inducible enhancer characteristics to the immediate-early IES (US3) promoter from human cytomegalovirus. J. Virol. 70: 5312-5328, 1996. PubMed: 8764042 Kolanus W , et al. alphaLbeta2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1 a cytoplasmic regulatory molecule. Cell 86: 233-242, 1996. PubMed: 8706128 Gan W , Rhoads RE . Internal initiation of translation directed by the 5'-untranslated region of the mRNA for eIF4G, a factor involved in the picornavirus-induced switch from cap-dependent to internal initiation. J. Biol. Chem. 271: 623-626, 1996. PubMed: 8557663 Tiffany HL , et al. Enhanced expression of the eosinophil-derived neurotoin ribonuclease (RNS2) gene requires interaction between the promoter and intron. J. Biol. Chem. 271: 12387-12393, 1996. PubMed: 8647842 Chan YJ , et al. Synergistic interactions between overlapping binding sites for the serum response factor and ELK-1 proteins mediate both basal enhancement and phorbol ester responsiveness of primate cytomegalovirus. J. Virol. 70: 8590-8605, 1996. PubMed: 8970984 Nauseel WM , et al. Effect of the R569W missense mutation on the biosynthesis of myeloperoxidase. J. Biol. Chem. 271: 9546-9549, 1996. PubMed: 8621627 Grune T , et al. Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome. J. Biol. Chem. 271: 15504-15509, 1996. PubMed: 8663134 Jondal M , Pross H . Surface markers on human b and t lymphocytes. VI. Cytotoxicity against cell lines as a functional marker for lymphocyte subpopulations. Int. J. Cancer 15: 596-605, 1975. PubMed: 806545 West WH , et al. Natural cytotoxic reactivity of human lymphocytes against a myeloid cell line: characterization of effector cells. J. Immunol. 118: 355-361, 1977. PubMed: 299761 Pross HF , et al. Spontaneous human lymphocyte-mediated cytotoxicity against tumor target cells. IX. The quantitation of natural killer cell activity. J.www.atcc360.com Clin. Immunol. 1: 51-63, 1981. PubMed: 7334070 Chen TR . Modal karyotype of human leukemia cell line, K562 (ATCC CCL 243). Cancer Genet. Cytogenet. 17: 55-60, 1985. PubMed: 3857109 Wu SQ , et al. Extensive amplification of bcr/abl fusion genes clustered on three marker chromosomes in human leukemic cell line K-56. Leukemia 9: 858-862, 1995.
　　中文名稱：人慢性髓原白血病細(xì)胞
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