5-氮雜-2'-脫氧胞苷, 98 %

??【編號】：119533

??【產(chǎn)品名稱】：5-氮雜-2'-脫氧胞苷, 98 %

??【規(guī)格】：5mg

??【用途】：

　　5-氮雜-2'-脫氧胞苷, 98 %

　　Product Name： 5-Aza-2′-deoxycytidine

　　CAS號：2353-33-5

　　分子式：C8H12N4O4

　　分子量：228.21

　　介紹： Decitabine is an epigenetic modifier that inhibits DNA methyltransferase activity which results in DNA demethylation (hypomethylation) and gene activation by remodeling "opening" chromatin. Genes are synergistically reactivated when demethylation is combined with histone hyperacetylation.Decitabine is an epigenetic modifier that inhibits DNA methyltransferase activity which results in DNA demethylation (hypomethylation) and gene activation by remodeling "opening" chromatin. Genes are synergistically reactivated when demethylation is combined with histone hyperacetylation.www.atcc360.com

　　生化和生理學(xué)機(jī)理： 5′-Azadeoxycytidine causes DNA demethylation or hemi-demethylation. DNA demethylation can regulate gene expression by "opening" the chromatin structure detectable as increased nuclease sensitivity. This remodeling of chromatin structure allows transcription factors to bind to the promoter regions, assembly of the transcription complex, and gene expression.

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5-氮雜-2'-脫氧胞苷, 98 %

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5-氮雜-2'-脫氧胞苷, 98 %

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