MMAD, ≥99%

??【編號(hào)】：125063

??【產(chǎn)品名稱】：MMAD, ≥99%

??【規(guī)格】：5MG

??【用途】：

　　MMAD, ≥99%

　　Product Name： MMAD

　　CAS號(hào)：203849-91-6

　　分子式：C41H66N6O6S

　　分子量：771.06

　　貯存：儲(chǔ)存溫度-20°C

　　可溶性： 25°C： DMSO

　　生化和生理學(xué)機(jī)理：

　　Description：

　　Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate.

　　For comparison purposes, the ADC A1 -mc-MMAD and/or A1 -vc-MMAD were used. The linker payload, mc-MMAD (6-maleimidocaproyl-monomethylauristatin-D) was conjugated to the A1 anti-5T4 monoclonal antibody through a cysteine residue at a ratio of approximately 4 drug moieties per antibody molecule. The linker payload mc- Val-Cit-PABA-MMAD or vc-MMAD (maleimidocapronic -valine-citruline-p- aminobenzyloxycarbonyl- monomethylauristatin-D) was conjugated to the A1 anti-5T4 monoclonal antibody through a cysteine residue at a ratio of approximately 4 drug moieties per antibody molecule (Antibody-drug conjugates Patent： WO 2013068874 A1).

上一篇：JANEX-1		下一篇：Tipranavir, ≥99%

MMAD, ≥99%

產(chǎn)品明細(xì)

熱銷產(chǎn)品 新品上架

產(chǎn)品推薦 相關(guān)產(chǎn)品

MMAD, ≥99%

產(chǎn)品明細(xì)

熱銷產(chǎn)品 新品上架

產(chǎn)品推薦 相關(guān)產(chǎn)品

　　MMAD, ≥99%

熱銷產(chǎn)品新品上架

產(chǎn)品推薦相關(guān)產(chǎn)品