GW4064, ≥99%
Product Name: GW4064
別名:Benzoic acid, 3-[2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]-
CAS號(hào):278779-30-9
分子式:C28H22Cl3NO4
分子量:542.84
介紹: GW4064
貯存: 儲(chǔ)存溫度-20°C
可溶性:
DMSO 109 mg/mL
Water <1 mg/mL
Ethanol <1 mg/mL
生化和生理學(xué)機(jī)理:
GW 4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).GW 4064 displays no activity at other nuclear receptors at concentrations up to 1 μM. GW 4064 improves hyperglycaemia and hyperlipidemia in diabetic db/db mice.