他米巴羅汀,≥99%
??【編號(hào)】:127943 ??【產(chǎn)品名稱】:他米巴羅汀,≥99% ??【規(guī)格】:1G ??【用途】: 他米巴羅汀,≥99%
Product Name: Tamibarotene
別名:4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoicacid
CAS號(hào):94497-51-5
分子式:C22H25NO3
分子量:351.44
介紹: Tamibarotene
貯存: 儲(chǔ)存溫度-20°C
可溶性:
DMSO 70 mg/mL
Water <1 mg/mL
Ethanol 70 mg/mL
生化和生理學(xué)機(jī)理:
Tamibarotene, Retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Tamibarotene exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 μM respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo.
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